I take Topamax for fibromyalgia -- 200 mg/day: 100 mg/a.m., 100 mg/p.m., and have been on it for about five months now. It has helped some with the pain, but I still need painkillers and muscle relaxers daily. Initially, 50 mg/day PO administered in 2 divided doses. Increase the daily dose by 50 mg once per week during weeks 2, 3, and 4. Increase the daily dose by 100 mg once per week during weeks 5 and 6; administer total daily dose in 2 divided doses. Topiramate reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI). Effects of Topamax on other antiepileptic medicinal products. The addition of Topamax to other AEDs (phenytoin, carbamazepine, valproic acid, phenobarbital, primidone) has no effect on their steady-state plasma concentrations, except in the occasional patient, where the addition of Topamax to phenytoin may result in an increase of plasma. TOPAMAX ® (topiramate) Tablets and Capsules. DESCRIPTION. Topiramate is a sulfamate-substituted monosaccharide. TOPAMAX ® (topiramate) Tablets are available as 25 mg, 50 mg, 100 mg, and 200 mg round tablets for oral administration. Is Topamax a Wonder Drug? Over the past week alone, I have talked to several people about their doctor visits. Each one of them had a different illness and each one of them was prescribed the drug Topamax. Making Sense of Antiepileptic Drugs in 2007 Thomas K. Koch, MD Ortho McNeil Pharmaceuticals Speakers Bureau Abbott Laboratories Speakers Bureau Topiramate, sold under the brand name Topamax among others, is a medication used to treat epilepsy and prevent migraines. It has also been used in alcohol dependence. For epilepsy this includes with generalized or focal seizures. It is taken by mouth. may cause tremors, dizzyness, muscle weakness and lack of coodination, a slow and slumped gait, extreme lethargy (tiredness), problems swallowing.. the list goes on. I was giving an example, most people are prescribed topamax at night because of its sedative effects. However i do have patients who are using it in the morning if they dont get a sedative effect after using it.